Fenton Lab

PI: Flavio Fenton

 

Papers

2020
2019
  • Iravanian S, Herndon C ,  Langberg JJ, Fenton FH . Theoretical Modeling and Experimental Detection of the Extracellular Phasic Impedance Modulation in Rabbit Hearts. Frontiers in physiology 10, 883
  • Dierckx H, Fenton FH, Filippi S, Pumir AJ,  Sridhar S. Simulating normal and arrhythmic dynamics: From sub-cellular to tissue and organ level. Frontiers in Physics 7, 89
  • Iravanian S, Herndon C,  Langberg JJ, Fenton FH. Theoretical Modeling and Experimental Detection of the Extracellular Phasic Impedance Modulation in Rabbit Hearts. Frontiers in physiology 10, 883
  • Kaboudian A,  Cherry EM,  Fenton FH. Real-time interactive simulations of large-scale systems on personal computers and cell phones: Toward patient-specific heart modeling and other applications. Science advances 5 (3), eaav6019
2018
  • Christoph J, Chebbok M, Richter C, Schroder-Schetelig J, Bittihn P, Stein S, Uzelac I, Fenton FH, Hasenfuss G, Gilmour RF, Luther S. “Electromechanical vortex filaments during cardiac fibrillation” Nature 555(7698): 2018.
  • Islam MA, Cleaveland R, Fenton FH, Grosu R, Jones PL, Smolka SA. “Probabilistic reachability for multi-parameter bifurcation analysis of cardiac alternans” Theoretical Computer Science, 2018
  • Muñoz LM, Gelzer ARM, Fenton FH, Qian W, Lin WY, Gilmour RF,  Otani NF. Discordant Alternans as a Mechanism for Initiation of Ventricular Fibrillation In Vitro. Journal of the American Heart Association 7 (17), e007898
  • Loppini A, Gizzi A, Ruiz-Baier R, Cherubini C, Fenton FH, Filippi S. Competing mechanisms of stress-assisted diffusivity and stretch-activated currents in cardiac electromechanics. Frontiers in physiology 9, 1714
2017
  • Cherry EM, Fenton FH, Krogh-Madsen T, Luther S, Parlitz U. “Introduction to Focus Issue: Complex Cardiac Dynamics” Chaos 27(9): 2017.
  • Barone A, Fenton FH, Veneziani A. “Numerical sensitivity analysis of a variational data assimilation procedure for cardiac conductivities” Chaos 27(9): 2017.
  • Cairns D, Fenton FH, Cherry EM. “Efficient parameterization of cardiac action potential models using a genetic algorithm” Chaos 27(9): 2017.
  • Ji Y, Uzelac I, Otani N, Luther S, Gilmour RF, Cherry EM, Fenton FH. “Synchronization as a mechanism for low-energy anti-fibrillation pacing” Heart Rhythm 14(8): 2017.
  • Gizzi A, Loppini A, Cherry EM, Cherubini C, Fenton FH, Filippi S. “Multi-band decomposition analysis: application to cardiac alternans as a function of temperature” Physiological Measurement 38(5): 2017.
  • Chen D, Gray RA, Uzelac I, Herndon C, Fenton FH. “Mechanism for amplitude alternans in electrocardiograms and the initiation of spatiotemporal chaos” Physical Review Letters 118(16): 2017.
  • Gurevich D, Herndon C, Uzelac I, Fenton FH, Grigoriev R. “Level-set Method for Robust Analysis of Optical Mapping Recordings of Fibrillation” Computing in Cardiology 44: 2017.
  • Uzelac I, Ji Y, Hornung D, Schroder-Scheteling J, Luther S, Gray R, Cherry EM, Fenton FH. “Simultaneous Quantification of Spatially Discordant Alternans in Voltage and Intracellular Calcium in Langendorff-Perfused Rabbit Hearts and Inconsistencies with Models of Cardiac Action Potentials and Ca Transients” Frontiers in Physiology 8(819): 2017.
  • Welsh A, Greco E, Fenton FH. “Dynamics of a human spiral wave” Physics Today 70(2): 2017.
2016
  • Ji YC, Fenton FH, “Numerical solutions to spatial and temporal partial di?erential equations: Application to neural and cardiac models” American Journal of Physics accepted, 2016
  • Fenton FH “Book review: Patterns in Excitable Media: Genesis, Dynamics, and Control” Physics today 69 (2), 48, 2016
  • Hoffman NJ, LaVigne NS, Scorse ST, Fenton FH, Cherry EM “Reconstructing three-dimensional reentrant cardiac electrical wave dynamics using data assimilation” Chaos 26 (1), 013107, 2016
  • Xue S, Lim H, Glimm J, Fenton FH, Cherry EM,  “Sharp Boundary Electrocardiac Simulations”  SIAM Journal on Scientific Computing 38 (1), B100-B117, 2016
2015
  • Bueno-Orovio A, Cherry EM, Evans SJ, Fenton FH “Basis for the Induction of Tissue-Level Phase-2 Reentry as a Repolarization Disorder in the Brugada Syndrome, 2015
  • Ji YC, Gray RA, Fenton FH “Implementation of Contraction to Electrophysiological Ventricular Myocyte Models, and Their Quantitative Characterization via Post-Extrasystolic Potentiation” PloS One 10 (8), e0135699, 2015
  • Islam MA, Murthy A, Bartocci E, Cherry EM, Fenton FH, Glimm J, Smolka SA, Grosu R. “Model-order reduction of ion channel dynamics using approximate bisimulation” Theoretical Computer Science 599, 34-46, 2015
  • Uzelac I, Fenton FH.  “Robust Framework for Quantitative Analysis of Optical Mapping Signal without Filtering.”  Computers in Cardiology, 461-464, 2015
  • Welsh AJ, “Snowbird Meeting Turns Chaotic: SIAM Dynamical Systems 2015 Conference Reveiw,” Dynamical Systems Today, 2015
2014
  • Filippi S, Gizzi A, Cherubini C, Luther S, Fenton FH “Mechanistic insights into hypothermic ventricular fibrillation: the role of temperature and tissue size” Europace, 16 (3), 424-434, 2014
  • Filippi S, Cherubini C, Gizzi A, Loppini A, Fenton FH “Spatio-temporal correlation of paced cardiac tissue”. Cardiovascular Oscillations (ESGCO) IEEE, 223-224, 2014
  • Garzon A, Grigoriev RO, Fenton FH “Continuous-time control of alternans in long Purkinje fibers”, Chaos 24 (3), 033124,  2014
  • Chen DD, Gray RA, Fenton FH “Modelling the take-off voltage of the action potential during fast pacing”, Computing in Cardiology Conference (CinC), 685-688 , 2014
  • Grosu R, Cherry EM, Clarke EM, Cleaveland R, Dixit S, Fenton FH, Gao S, Glimm J, Gray RA, Mangharam R, Ray A, Smolka SA “Compositional, approximate, and quantitative reasoning for medical cyber-physical systems with application to patient-specific cardiac dynamics and devices Leveraging Applications of Formal Methods, Verification and Validation. Specialized Techniques and Applications 356-364, 2014
2013
  • Bragard J, Elorza J, Cherry EM, Fenton FH “Validation of a computational model of cardiac defibrillation.” Computing in Cardiology (CinC), 851-854, 2013
  • Uzelac I, Holcomb M, Reiserer RS, Fenton FH, Wikswo JP “High-power current source with real-time arbitrary waveforms for in vivo and in vitro studies of defibrillation.” Computing in Cardiology (CinC), 667-670, 2013
  • Kelly A, Ghouri IA, Kemi OJ, Bishop MJ, Bernus O, Fenton FH, Myles RC, “Subepicardial action potential characteristics are a function of depth and activation sequence in isolated rabbit hearts.” Circulation: Arrhythmia and Electrophysiology,6 (4), 809-817, 2013
  • FH Fenton, A Gizzi, C Cherubini, N Pomella, S Filippi “Role of temperature on nonlinear cardiac dynamics.” ,Pysical Review E 87 (4), 042717, 2013
  • Murthy A, Bartocci E, Fenton FH, Glimm J, Gray R, Cherry RM, Smolka S,  “Curvature analysis of cardiac excitation wavefronts.” Computational Biology and Bioinformatics, IEEE/ACM Transactions, 2013
  • Bragard J, Marin S, Cherry EM, Fenton FH  “Study of Cardiac Defibrillation Through Numerical Simulations.” Without Bounds: A Scientific Canvas of Nonlinearity and Complex Dynamics, 2013
  • Gizzi A, Cherry EM, GilmourJr RF, Luther S, Filippi S, Fenton FH “Effects of pacing site and stimulation history on alternans dynamics and the development of complex spatiotemporal patterns in cardiac tissue.” Frontiers in physiology, 4, 2013
2012
  • Cherry EM, Fenton FH.  “Contribution of the Purkinje network to wave propagation in the canine ventricle: insights from a combined electrophysiological-anatomical model.” Nonlinear Dynamics 68 (3), 68 (3), 365-379, 2012
  • Cherry EM, Fenton FH, Gilmour RF “Mechanisms of ventricular arrhythmias: a dynamical systems-based perspective.” American Journal of Physiology-Heart and Circulatory Physiology, 2012
  • Murthy A, Islam M, Bartocci E, Cherry EM, Fenton RH, Glimm J, “Approximate bisimulations for sodium channel dynamics.” Computational Methods in Systems Biology, 267-287, 2012

 

Awards

  • Petit scholar award (Neil Hardy, 2015-2106)
  • Petit mentor award (Conner Herndon, 2015-2106)
  • GoSTEM Faculty Fellow award (Fenton 2015-2016)
  • PURA Salary Award (James Timothy Farmer, 2016)
  • PURA Slaray Award (Madeline Lazar, 2016)
  • Physics REU at UCLA (Krishgma Singal, 2016)
  • APS March Meeting Top Presenter, SPS (Krishma Singal, 2016)
  • College of Science Mehta Phingbodhipakkiya Award (Krishma Singal, 2016)
  • National Academy of Sciences Mirzayan Science & Technology Policy Fellowship (Yanyan Ji, 2016)
  • PURA Salary Award (Casey Trimble, 2015)
  • PURA Salary Award (Mary Elizabeth Lee, 2015)
  • PURA Salary Award (Krishma Singal, 2015)
  • PURA Salary Award (Ramprasath Rajagopal, 2015)
  • Physics REU at William and Mary, (Mary Elizabeth Lee, 2015)
  • Best Poster Award, REU W&M (Mary Elizabeth Lee, 2015)
  • GT URSA award (Krishma Singal, 2015)
  • Hesburgh Award Teaching Fellow (Fenton 2014).
  • CETL/BP Junior Faculty Teaching Excellence Award (Fenton 2104).
  • Women’s Leadership award, (Andrea Welsh, 2014)
  • Silver medal at the 2014 University Physics Competition (Casey Trimble, 2014)
  • PURA award (Amier Naji, 2014)
  • Physics REU at GT (Casey Trimble, 2014)
  • ITT Instructure of the quarter award (Ilija Uzelac, 2014)
  • AAPT Outstanding Teaching Assistant Award (Andrea Welsh, 2014)
  • GT Diversity Championship Award (Andrea Welsh, 2014)
  • Travel Awards:
    1)  Okinawa Integrative Biology Course, Japan. (Elisa Nuzes Acosta, 2013)
    2)  APS SPS travel award, meeting at Puerto Rico (Casey Trimble, 2014)
    3)  AMS workshop on Integrating Dynamics and Stochastics, Brown U. (Casey Trimble, 2014)
    4)  SIAM Travel award, Dynamical Systems, Utah  (Andrea Welsh, 2014)
    5)  V SUMMER SCHOOL ON STATISTICAL PHYSICS OF COMPLEX AND SMALL SYSTEMS, Barcelona (Diandian Chen, 2015)
    6)  V SUMMER SCHOOL ON STATISTICAL PHYSICS OF COMPLEX AND SMALL SYSTEMS, Barcelona (Jairo Rodriquez, 2015)
    7)  Dynamics of Coupled Oscillators: 40 years of the Kuramoto Model Workshop , Dresden Germany (Andrea Welsh, 2015)
    8)  NAS Frontiers in Physics, Pattern Formation, and Complex Materials Far From Equilibrium, DC (Andrea Welsh, 2015)
    9)  Experimental chaos and Complexity meeting, Canada (Conner Herndon, 2016)
    10) SIAM life Scieces meeting (Andrea Welsh, 2016)
    11) PURA Travel Award (Krishma Singal, 2016)
    12) PURA Travel Award (Mary Elizabeth Lee, 2016)

 

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